Research translation, accelerated

TIA invests in translational research infrastructure to enable seamless access to expertise and services vital to translate research discoveries into human health impacts. Our investment in people and capital lowers the financial bar to access expertise for all translational researchers, including academics, clinicians, medical research institutes and small-medium enterprises. Through initiatives such as the Pipeline Accelerator and Technical Feasibility Assessment voucher schemes, we also provide targeted funding support to fast-track promising projects. Our mission is to support and develop a vibrant and productive Australian Research and Development ecosystem.

The TIA consortium is enabled by the National Collaborative Research Infrastructure Strategy.

The TIA network

TIA enables open and subsidised access to a broad range of expertise across various therapeutic types (see left). Each area is supported by a dedicated broker/facilitator with relevant know-how and experience in areas such as research, clinical trials, translation and manufacturing. These facilitators ensure a smooth process of directing projects to the correct facility, advising and mentoring researchers, and supporting collaboration within and between capabilities.

To browse our accessible capabilities or find a specific facility, click the links below.

TIA at a glance

$116.6M

invested in facilities since 2018

35

accessible facilities in universities hospitals and research institutes

636

therapeutic development projects in progress

35

cleanrooms for manufacturing

218

expert scientists and
technicians supported

247

access vouchers awarded totalling $8.6M

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Biologics and Vaccines

Discovery and devlopment of advanced biotherapeutics

Our Biologics and Vaccines capability supports therapeutic discovery, from screening of antibody libraries and production of  recombinant proteins as small-molecule drug targets, through to novel, engineered biologics, vaccine antigens and diagnostic reagents, from discovery through to the scale-up and manufacturing of clinically-relevant material.

Facilities:

  • National Biologics Facility, UQ
  • CSIRO Biomanufacturing
  • Protein Expression Facility, UQ*
  • Recombinant Protein Facility, UNSW*
  • Biologics Innovation Facility, UTS*

* Accessible via TIA Voucher

Small Molecule Therapeutics

Integrated drug discovery and development

Small Molecule Therapeutics is a long-established pipeline of complementary capabilities supporting translation of projects from hit identification to preclinical efficacy testing. We offer access to compound libraries, high-throughput screening technologies and specialist development and preclinical expertise.

Facilities:

  • CSIRO Biomanufacturing
  • AB Initio Pharma*
  • Centre for Integrated Preclinical Drug Development, UQ
  • Qld Emory Drug Discovery Inititiative, UniQuest
  • Compounds Australia, Griffith 
  • Australian Translational Medicinal Chemistry Facility, Monash
  • Centre for Drug Candidate Optimisation, Monash
  • MMIC, Monash *
  • Drug Target Identification, Monash Universtity*

Screening facilities:

  • National Drug Discovery Centre, WEHI 
  • Monash Functional Genomics Platform, Monash*
  • Functional Genomics South Australia, Uni of Adelaide*
  • CO-ADD, Monash*
  • Discovery Biology, Griffith*
  • ACRF Drug Discovery Centre for Childhood Cancer, Children’s Cancer Institute*
  • IBN Nathan Mass Spec Facility, Griffith*
  • Stafford Fox Drug Discovery Facility, MCRI*
  • Monash Fragment Platform, Monash*
  • Cell Function & Screening Facility, VCCRI Innovation Centre*
  • ANU Centre for Therapeutic Discovery, ANU*
  • Victorian Centre for Functional Genomics, Peter Mac*

* Accessible via TIA Voucher

Cell & Gene therapies

Development and testing of advanced therapeutic medicinal products

TIA brings together key national cell and gene therapy development and manufacturing facilities to enable development of cutting-edge advanced therapies. Our consortium has broad and deep expertise to support your project regardless of your project’s stage of development.

Facilities:

  • Cell Therapies Pty Ltd*
  • Cell & Tissue Therapies WA, RPH
  • Cell and Molecular Therapies, Royal Prince Alfred Hospital
  • Sydney Cell & Gene Therapies, Westmead Precint
  • Functional Genomics South Australia*
  • Vector & Genome Engineering Facility, CMRI*
  • Centre of Excellence in Cellular Immunotherapy, PeterMac* 
  • Q-Gen Cell Therapies, QIMR Berghofer

* Accessible via TIA vouchers

RNA Products

Support for cutting edge therapeutics

Our RNA Products Capability enables end-to-end mRNA vaccine and therapeutics development within Australia, providing a vibrant and productive pipeline built by onshore researchers – and complementing emerging commercial RNA service providers. We enable access to extensive experience in the design and production of high quality mRNA and synthetic RNA (e.g. siRNA, aptamers and guide RNA) with modified nucleotides, 5-cap and lipid nanoparticles (LNP) formulation for in vitro and in vivo studies.

Facilities:

  • BASE RNA Facility, UQ
  • mRNA CORE, Monash
  • RNA Institute, UNSW
  • RNA Innovation Foundry, UWA

* Accessible via TIA Voucher