Our Vision

All Australian researchers will have access to world class translational research infrastructure to develop new therapeutics for human health.

Our Mission

The TIA consortium enables and accelerates the translation of research discovery along the therapeutic development pipeline by ensuring world class research infrastructure facilities are accessible to the Australian translational research community.

What we do

Established in 2008, Therapeutic Innovation Australia is the lead agent for the NCRIS "Therapeutic Innovation Australia" project funded by the Australian Department of Education, Skills and Employment. ​TIA invests in soft and hard infrastructure at national facilities to support and enable access to translational research facilities that can accelerate translation of discoveries from the lab to the clinic. Our consortium members provide a wide range of translational services. TIA works to lower the bar for researchers to access excellent translational research services in the fields of biologics, cell and gene therapies, small molecules and clinical trials.

The NCRIS network supports national research capability through the employment of 1,700 highly skilled experts across 23 facilities. NCRIS facilities are accessed by over 35,000 researchers from academia and industry, within Australia and from overseas.

Infographic: Where TIA fits in the Therapeutic Development priority of the 2016 Roadmap. D1-T4 is intended to codify the therapuetic development pipeline from discovery (D1-4) to translation (T1-4). In summary:
D1   -   Basic research ti establish fundamental biologic mechanisms
D2   -   Disease biology research to identify potential therapeutic targets 
D3   -   Therapeutic agent discovery eg. HTS, phage display, gene therapy development
D4   -   Therapeutic agent development inc. preclinical testing
T1    -   Translation to humans (eg. Phase I)
T2    -   Translation to patients (eg. Phase II,III)
T3    -   Translation to practice
T4    -   Translation to populations
D1-D4 adapted from Gannon, F. (2014) the steps from translatable to translational research. EMBO Reports 15(11):1107-1108. 
T1-T4 adapted from Harvard Catalyst Pathfinder website (http://catalyst.harvard/edu/pathfinder)