Improving efficiency of clinical trial registration
The Australian New Zealand Clinical Trials Registry (ANZCTR) is an on-line registry (www.anzctr.org.au) of clinical trials being undertaken in Australia, New Zealand and worldwide, and contributes data to the World Health Organization’s International Clinical Trials Registry Platform. The ANZCTR has various users and stakeholders, with the challenge being to constantly improve the usability and efficiency of the registration process without compromising quality and completeness, so that it can remain an invaluable resource for patients, regulators, researchers, and policy-makers, both nationally and internationally. This improvement of registry usability form part of the aim to enable increasing trial registration, which is encouraged by the World Health Organization, World Medical Association’s Helsinki Declaration, and many governments around the world.
How did the facility help
The ANZCTR team has worked extensively on devising logic rules in order to increase automation for users when completing the registration form. Essentially a series of internal checks are applied to the information entered by the registrant, and if there are any inconsistencies, a prompt will automatically appear advising the registrant to correct the error.
Since implementation of this function on 4th October, 2016, there has been a noticeable decrease in the amount of querying required by staff, particularly for update submissions. From January to September, 2016, approximately 45% of updates were able to be approved without any querying required from staff. From October 2016 to January 2017, this proportion increased to 62% (see figure below). This not only reduces staff workload, but also saves time for the registrant, who does not have to login and address queries. The team will continue to devise additional logic rules where possible to increase automation and efficiency.
The ANZCTR is an on-line registry (www.anzctr.org.au) of clinical trials being undertaken in Australia, New Zealand and worldwide, and contributes data to the World Health Organization’s International Clinical Trials Registry Platform. The Registry was established in mid-2005 and is housed at the NHMRC Clinical Trials Centre, University of Sydney. It is publicly available, to search or enter data, 24 hours a day, 7 days per week.
The ANZCTR forms one of the key platforms in Australia’s national research infrastructure, ensuring Australia takes responsibility for the oversight of health and medical research conducted within its borders, and it helps ensure Australians and New Zealanders meet their ethical and international obligations for research transparency.